“Kinetic properties of the cardiac L-type Ca2+ channel and its role in myocyte electrophysiology: a theoretical investigation”. Related article: Faber GM, Silva J, Livshitz L, Rudy Y. ♦ LRd with Markov L-type Ca 2+ channel and Ryanodine receptor, 2007 Epub 2007 Feb 2.ĭownload: Matlab code for LRd Matlab code for HRd “Regulation of Ca 2+ and electrical alternans in cardiac myocytes: role of CAMKII and repolarizing currents”. ♦ LRd/HRd with role of CaMKII and alternans, 2007 “Role of activated CaMKII in abnormal calcium homeostasis and I(Na) remodeling after myocardial infarction: insights from mathematical modeling”. Related article: Hund TJ, Decker KF, Kanter E, Mohler PJ, Boyden PA, Schuessler RB, Yamada KA, Rudy Y. ♦ HRd model for abnormal Ca 2+ homeostasis, 2008 Related article: Decker KF, Heijman J, Silva JR, Hund TJ, Rudy Y, “Properties and Ionic Mechanisms of Action Potential Adaptation, Restitution and Accommodation in Canine Epicardium” Am J Physiol Heart Circ Physiol 2009 296:1017-1026. ♦ HRd single cell and strand rate-dependent behaviors and restitution, 2009 “Uniqueness and stability of action potential models during rest, pacing, and conduction using problem-solving environment”. “Contributions of ion channel currents to ventricular action potential changes and induction of early afterdepolarizations during acute hypoxia”. “Ionic mechanisms of electrophysiological heterogeneity and conduction block in the infarct border zone”. ♦ HRd model for infarct border zone, 2010 “Multiscale modeling of calcium cycling in cardiac ventricular myocyte: macroscopic consequences of microscopic dyadic function”. ♦ Local stochastic Ca 2+ release processes, 2011

“Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient”. Related article: Heijman J, Volders PG, Westra RL, Rudy Y. “A model of canine purkinje cell electrophysiology and Ca 2+ cycling: rate dependence, triggered activity, and comparison to ventricular myocytes”.

“Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation”. Related article: O’Hara T, Virág L, Varró A, Rudy Y. ♦ ORd orginal human ventricular model, 2011 (Please click the following links to download codes ) List of Models for Ion Channels, Myocytes and Regulatory Pathways

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